Dear members and friends of the MPN Advocates Network, Today, we have launched MPN Horizons 2022! We are delighted to be reunited in Netanya, Israel, the home town of our beloved Giora Sharf. We have discussed the following highlights so far: Starting off with Werner Zinkand introducing the event, followed by Claire Harrison joining live on zoom. A very warm welcome was given by Giora Sharf to the beautiful city of Netanya.   The opening of #MPNHZ22 ended with the MPN AN Update given by our Steering Committee member Jon Mathias. The first session covered regional reports and presentations from the regional leaders. The afternoon sessions kicked off with a brilliant scientific talk on Progression and mutations given by Martin Ellis, followed by a talk on Diagnosing MPNs by Naveen Pemmaraju and finishing the session with the talk on Comorbidities in MPNs by Gabriela Hobbs. We finished off day 1 of MPN Horizons 2022 Hybrid with an impressive examples of best practice in advocacy from our members worldwide. More exciting activities coming tomorrow! @GMPNAN #MPNHZ22